Edward Jenner was a doctor in Berkeley, Gloucestershire. In 1796 he carried out his now famous experiment on eight-year-old James Phipps. Jenner inserted pus taken from a cowpox pustule on the hand of milkmaid Sarah Nelmes and inserted it into an incision on the boy's arm. He was testing his theory, drawn from the folklore of the countryside, that milkmaids who suffered the mild disease of cowpox never contracted smallpox.
